Barbara Wong left her role as managing director within investment banking at Barclays on Friday, a spokeswoman for the UK bank confirmed.
It is unclear where Wong, who was with the bank for about three years, is headed but according to one person familiar with the matter she has resigned and is likely headed to a rival firm.
Wong, who was based in Hong Kong, had mainly been involved in China and Taiwanese M&A deals. Among the China deals Barclays has been involved in are acting as an adviser to US hog producer Smithfield Food, which was acquired by Shuanghui International last year.
This year, it advised Chinese internet company Tencent on its acquisition of a stake in JD.com.
Wong had previously worked as an executive director at Morgan Stanley for more than two years, according to her Linked-In profile and, prior to that, was a vice-president at Credit Suisse, where she worked for more than four years.
She is leaving Barclays at a time when the bank has seen changes at the helm of the M&A team and an overhaul within its investment bank.
On the M&A side, Vanessa Koo was named head of Asia-Pacific mergers and acquisitions in June, replacing Edward King, who moved to the US to take on a new role as executive chairman of global M&A earlier this year but who subsequently left the bank.
In May, Jason Rynbeck, vice-chairman of M&A for the region, left Barclays and started work at HSBC this month as its new head of M&A for Asia-Pacific.
Barclays last month named Patrick Kwan as co-head of investment banking for Asia Pacific. He shares the role with Reid Marsh, who was relocated from London this month. The pair replaced Matthew Ginsburg, who stepped down from his role as regional head of investment banking in May to take up a position with Barclays outside the region
In July, Barclays also reorganised its industry coverage teams, promoting internally to fill several senior positions left vacant in Asia after a spate of recent departures.
The changes included announcing heads for the newly-combined industrials, power & utilities group; natural resources, financial institutions group, and technology, media and telecommunications for the Asia Pacific region.
